The Texas Department of State Health Services (DSHS) has issued a warning about the risks associated with products containing 7-hydroxymitragynine (7-OH), a substance found in the kratom plant that acts similarly to opioids. According to DSHS, high concentrations of 7-OH can lead to significant health issues and carry the potential for dependence or abuse.
As of August 27, the Texas Poison Center Network had recorded 192 reports in 2025 involving exposure to kratom or other products containing 7-OH. This marks an increase from previous years, with 107 cases reported in all of 2024 and 122 in all of 2023. Of this year’s reports, 19 involved exposure to concentrated forms of 7-OH, with most incidents occurring during July and August. Eleven people required treatment at healthcare facilities after being exposed to these concentrated products.
“Kratom is a tropical tree native to Southeast Asia. Kratom and 7-OH products are sometimes marketed as natural remedies for pain, anxiety, or to help with opioid withdrawal. Kratom products typically contain low 7-OH concentrations (less than 2% total content or less). However, semi-synthetic or synthetic 7-OH products have concentrations up to 98% 7-OH and are now more readily available. Concentrated 7-OH is often added to kratom products. Because of its opioid-like characteristics, there is significant potential for abuse of 7-OH at concentrated levels. In studies, 7-OH shows up to 13 times the potency of morphine, an opioid pain-relieving medication. Products containing concentrated 7-OH are sold as pills, gummies, candies, and imitation ice cream cones at gas stations, smoke shops, and online,” according to DSHS.
The U.S. Food and Drug Administration took steps in July 2025 aimed at restricting access to these substances due to their strong opioid-like effects. Neither kratom nor products containing concentrated amounts of its chemical compounds have been approved by the FDA for medical use.
Symptoms reported after using products containing high levels of 7-OH include nausea and vomiting, agitation, confusion, sweating, rapid heart rate, high blood pressure, trouble breathing, sleepiness or loss of consciousness, seizures, and respiratory depression.
Healthcare providers are advised by DSHS: “Provide general emergency and critical care medical support as warranted. Administer naloxone for reversal of respiratory depression. Observe and manage symptoms of opioid use disorder following use of kratom or 7-OH products. Contact the Texas Poison Center Network at 1-800-222-1222 for any questions about medical management.”
DSHS also advises the public: “Avoid all products containing 7-OH, including products that claim to treat a health ailment. Examine the packaging and label when buying candies and other treats. Keep kratom and 7-OH products away from children and pets. Talk to children and teens about the dangers of 7-OH and kratom products. Consult a doctor or pharmacist before using any supplements, especially ones marketed for pain, energy, or mood. Talk to a health care provider if help is needed with opioid addiction, anxiety, mood disorders, pain or other ailments. Contact a health care provider or call the Poison Help Line at 1-800-222-1222 regarding concerns about 7-OH.” In case someone is unresponsive or needs urgent medical attention after possible exposure to these substances,“Call 9-1-1 immediately.”
For additional questions regarding adverse reactions or reporting related events from use of kratom or concentrated forms like 7-OH products in Texas contact the Texas Poison Center Network at 1-800-222-1222 or report adverse events via 1-800-332-1088.
